Package: SlideCNA 0.1.0

SlideCNA: Calls Copy Number Alterations from Slide-Seq Data

This takes spatial single-cell-type RNA-seq data (specifically designed for Slide-seq v2) that calls copy number alterations (CNAs) using pseudo-spatial binning, clusters cellular units (e.g. beads) based on CNA profile, and visualizes spatial CNA patterns. Documentation about 'SlideCNA' is included in the the pre-print by Zhang et al. (2022, <doi:10.1101/2022.11.25.517982>). The package 'enrichR' (>= 3.0), conditionally used to annotate SlideCNA-determined clusters with gene ontology terms, can be installed at <https://github.com/wjawaid/enrichR> or with install_github("wjawaid/enrichR").

Authors:Diane Zhang [aut, cre], Johanna Klughammer [aut], Jan Watter [aut], Broad Institute of MIT and Harvard [cph, fnd]