SlideCNA - Calls Copy Number Alterations from Slide-Seq Data
This takes spatial single-cell-type RNA-seq data
(specifically designed for Slide-seq v2) that calls copy number
alterations (CNAs) using pseudo-spatial binning, clusters
cellular units (e.g. beads) based on CNA profile, and
visualizes spatial CNA patterns. Documentation about 'SlideCNA'
is included in the the pre-print by Zhang et al. (2022,
<doi:10.1101/2022.11.25.517982>). The package 'enrichR' (>=
3.0), conditionally used to annotate SlideCNA-determined
clusters with gene ontology terms, can be installed at
<https://github.com/wjawaid/enrichR> or with
install_github("wjawaid/enrichR").